In 1803 President Jefferson directed Lewis and Clark to explore the vast Louisiana Purchase and the Northwest Passage to the Pacific Ocean. They traveled by keelboat and long canoes up the Missouri River starting in St Louis where it meets the Mississippi. By roadtrek, we tracked them to beautiful Kansas City. Now we're following the "Mighty Mo" up the Iowa/Nebraska border to South Dakota and beyond, where the longest river in North America flows through the Great Plains.